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A: It depends on different products

79 KamezakiY.EnomotoC.IshikawaY.KoyamaT.NayaS.SuzukiT.et al (2010)

Kanitz, M., et al., Insufficient glycemic control increases nuclear factor-kappa B binding activity in peripheral blood mononuclear cells isolated from patients with type 1 diabetes

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According to Ma and Farny (2023), senescence phenotypes in post-mitotic neurons cellular senescence are pronounced in enhanced activity of senescence-associated beta-galactosidase (SA--gal), cell cycle arrest [P53-P21 pathway and P16 pathway integrate to RB (retinoblastoma) hypophosphorylation], DNA damage, elevated RB hypophosphorylation, SASPs, and also senescence-associated heterochromatic foci (SAHFs), promoting cell cycle arrest (Ma and Farny, 2023

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